Rehabilitation Of Completely Edentulous Patients - A University Based Study
Jerusha Santa Packyanathan1, Padma Ariga2*, Ganesh Jeevanandan3
1 Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai – 600 077, TN, India.
2 Professor, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600077, Tamil Nadu, India.
3 Reader, Department of Pedodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600077, Tamil Nadu, India.
*Corresponding Author
Padma Ariga,
Professor, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai
- 600077, Tamil Nadu, India.
Tel: 9381041945
E-mail: padma@saveetha.com
Received: May 28, 2021; Accepted: June 16, 2021; Published: July 03, 2021
Citation:Jerusha Santa Packyanathan, Padma Ariga, Ganesh Jeevanandan. Rehabilitation Of Completely Edentulous Patients - A University Based Study. Int J Dentistry Oral Sci. 2021;8(7):3016- 3021.doi: dx.doi.org/10.19070/2377-8075-21000614
Copyright: Padma Ariga©2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Conventional complete dentures are supported by the edentulous ridges and the mucosa that overlies them. There is close contact, but no direct attachment between the prosthesis and the ridges, and the prostheses are constructed to maximise any potential retentive forces whilst attempting to minimise those that displace them. In such an active, muscularly-controlled environment this is problematic, and many patients have difficulties adapting to their dentures, particularly the lower denture. The main aim of this cross-sectional study is to evaluate the number of completely edentulous patients willing for implant supported fixed prosthesis. This is a record based study with a sample size of 365. The present study was conducted among edentulous patients who visited the outpatient department at the institution. The data was collected from the patient records. The data was categorised into age groups, gender, preference for fixed or removable prosthesis and type of fixed prosthesis. The coding was done in MS excel. The data was transferred to a host computer and processed using SPSS software version 21.0 (SPSS Inc., Chicago, IL, USA) by tabulation and graphical illustration. Descriptive statistics and chi square test was used to study the data collected and to analyse frequency distribution. The results showed that, of all the edentulous patients, only 3.8% wanted implant prosthesis and 96.2% wanted conventional complete dentures (CCD). Of the patients who preferred implant supported prosthesis 42% of them preferred screw retained prosthesis, followed by cement retained 35%, followed by overdenture 14% and 7% hybrid prosthesis. There is however, no significant association between gender and patients opting for full mouth rehabilitation(FMR) with implant prosthesis, but significant association is seen between age and patients preferring FMR.
2.Introduction
6.Conclusion
8.References
Keywords
Completely Edentulous Patients; Implant Supported Prosthesis; Patient Preference; Quality Of Life.
Introduction
tered
in dental practice. Oral rehabilitation in such patients is essential
to restore function and aesthetics [1]. Accumulation of calculus
over long periods of time along with bad oral hygiene habits
can lead to severe loss of alveolar bone and soft tissue resulting
in recession and ultimately severe periodontitis [2]. The end result
is the loss of natural teeth due to mobility caused by severe bone
loss [3]. Heavy smokers often have very poor or compromised
periodontium and are candidates for chronic advanced periodontitis.
In such patients full mouth extraction is done and is followed
by full mouth rehabilitation [4]. Complete dentures for patients
who are completely edentulous can be either removable or fixed.
Fixed prostheses are supported by dental implants and removable
prostheses are held by capillary action and adhere to soft tissue
[5]. In patients with narrow or resorbed ridge, connective tissue
grafts, bone augmentation, ridge augmentation, ridge split or sinus
lift can be done to accommodate implants [6].
Completely edentulous patients lack ability to masticate food
which leads to lack of nutritional intake. they have to modify their
food choices, especially when eating in a social environment, because
of the limitations of their dentures. Evidence also suggests
that if patients are challenged to eat a different range of foods, their current satisfaction with their conventional dentures is reduced.
Patients’ social interactions can be negatively affected by
conventional dentures. To overcome this, dental prosthesis which
is fixed or removable in nature reinforced by implant is fabricated
for the patient. People report avoiding going out to eat, being
self-conscious of the presence of others as they feel they may
notice them moving in the mouth when talking, eating or laughing
and because they may find it difficult to wear their dentures for a
prolonged period of time. Lip biting can cause dislodgement of
the denture [7].
Completely edentulous patients can be rehabilitated with fixed
prosthesis using osseointegrated implants. Full mouth rehabilitation
is done in periodontally compromised patients after full
mouth extraction. Implants can be placed in three weeks after
extractions with less waiting time for bone healing in order to
minimize surgical visits. In cases of loss of gingival tissues the
missing tissue can be compensated with composite resin which
is an artificial gingival material. This is an alternative to pink porcelain
which is lighter in weight [8]. Case reports of full mouth
rehabilitation are also done in patients with ectodermal dysplasia
have been documented [9]. In contrast to conventional denture
wearers, when encouraged to modify their diet, the satisfaction
with their prosthesis of those wearing implant overdentures is
shown to increase [10]. Previously our team has a rich experience
in working on various research projects across multiple disciplines
[11-25]. Thus the aim of this study was to evaluate the number
of completely edentulous patients willing for implant supported
fixed prosthesis.
Materials And Methods
Study setting
In this retrospective study, data from 365 patients within the institution
were collected from dental records. At data extraction, all
information was anonymized and tabulated onto a spreadsheet.
The study was commenced after approval from the Institutional
Review Board. The ethical approval number for the study was
SDC/SIHEC/2020/DIASDATA/0619 - 0320.
Data collection and/tabulation
To fulfil the inclusion criteria, patients who were completely edentulous
were included in the study. The preference for fixed or
removable prosthesis was assessed in these patients. Patients who
were partially edentulous and those unwilling for the study have
been excluded.
Sampling
Data were collected from June 2019 to March 2020 for 365 patients
who were completely edentulous and chose to have either
conventional complete dentures or implant supported prosthesis.
The following data were retrieved from the dental records: patient
age, gender and preference for fixed or removable prosthesis. The
data collected was analysed for the type of fixed prosthesis preferred.
Statistical analysis
The data was transferred to a host computer and processed using
SPSS software version 21.0 (SPSS Inc., Chicago, IL, USA).
Descriptive and inferential statistics was used to compare the type
of type of prosthesis with the age and gender of the patient. The
significance level was set at 5% for the present study.
Results
The data collected was analysed using IBM SPSS software. The
results are as follows.
Figure 1: Bar diagram representing age distribution of completely edentulous patients. X-Axis represents the age group distribution of completely edentulous patients and Y axis represents the percentage distribution with different age groups. The percentage distribution shows maximum number of edentulous patients (43.2%) were between were 60-69 years (orange), 26% were between 50- 59 years (green), 18.3% were 70 years and above (yellow), 9.3% were between 40-49 years (red) and the least (3.3%) were between 30-39 years (blue).
Figure 2: Bar diagram representing the comparison between the age distribution of study subjects and preference for FMR prosthesis. X-Axis represents the percentage distribution in each age group and Y axis represents the percentage of completely edentulous patients. Chi square test was done and association between age and preference for FMR was found to be statistically significant. (Pearson’s chi square value 18.885, df - 4, p value = 0.001- significant). This shows there is association between the age of the completely edentulous patient and the preference for type of prosthesis. The preference for conventional complete denture (blue) was highest (42.35%) among 60-69 years age group and for implant supported prosthesis (red) it was highest (1.64%) among 50-59 years.
Figure 3: Pie chart representing gender distribution of completely edentulous patients. It is seen that shows that the number of males (59.02% ; blue) were more edentulous than females (40.98% ; red).
Figure 4: Bar diagram representing the comparison between the gender distribution of study subjects and preference for FMR prosthesis. X-Axis represents the percentage distribution in each gender and Y axis represents the percentage of completely edentulous patients. Chi square test was done and association between gender and preference for FMR was found to be statistically insignificant (Pearson’s chi square value 0.167, df - 4, p value = 0.683- not significant). However, males (56.56%) outnumbered females (2.46%) in terms of preference for conventional complete denture (blue). The preference for implant supported prosthesis (red) was also higher among males (2.46%) than females (1.37%).
Figure 5: Bar diagram representing preference of FMR prosthesis in completely edentulous patients. X-Axis represents the preference of FMR prosthesis and Y axis represents the percentage distribution among completely edentulous. A higher percentage of 96.2% opted for conventional complete denture (blue) than 3.8% who preferred implant supported prosthesis (red).
Figure 6: Bar diagram representing arch distribution of completely edentulous patients with FMR. X-Axis represents the arch distribution of patients and Y axis represents the percentage distribution among different completely edentulous arches. The percentage distribution shows 42.9% had implant supported prothesis in both maxilla and mandible, the same percentage opted for implant supported prosthesis (42.9%) in mandible only but only 14.3% for implant supported prosthesis in maxilla only (red).
Figure 7: Bar diagram representing type of FMR prosthesis distribution in completely edentulous patients. X-Axis represents the type of FMR prosthesis and Y axis represents the percentage distribution among different types of FMR prosthesis. The percentage distribution shows the most preferred type of prosthesis (42.9%) was screw retained (red), followed by 35.7% cement retained prosthesis (blue), 14.3% had over dentures (green) and 7.1% had hybrid prosthesis (orange).
Discussion
In our study it was noted that the highest number of complete
denture wearers were between the age of 60-69 years. This is in
accordance with another study which showed the average age of
complete denture patients in their study was 67.3 years [26]. Another
study states an increase in patients older than 55 years wearing
dentures [27]. In our study, the number of completely edentulous
male patients (56.4%) outnumbered female patients (43.6%).
This is in contradiction to another study that states, women are
more likely to be edentulous than are men [28]. This could be
because periodontal disease was predominant in women when
compared to men [29, 30].
In our study, 96.2% of the subjects chose the conventional complete
denture over an implant supported prosthesis. Magnetic
prosthesis is available but was not fabricated for any patient in
our study [31]. Although implant supported prostheses are gaining
popularity, the results from the present study indicated that
the CCD is the preferred treatment of choice and most patients
were more likely to opt for minimum, low stress and low-cost
interventions. A preference by patients for simpler intervention within their financial capacity is of major concern especially for
older edentulous subjects is common in clinical practice [32]. Patients’
disapproval of an extended treatment period was also mentioned
by Kaptein [33]. Techniques that reduce the time required
for completion of treatment, such as the immediate loading of
implants for overdentures [34]. Cost and attitudes towards cost
are the most important barriers to the utilization of dental care.
This remains a very real perceived barrier to the delivery of implant
supported prostheses. On the other hand, the most common
and most highly rated reason for refusal of implants was
concern about surgical risks, even when there was no financial
cost, indicating that choices involving surgery may cause anxiety
and uncertainty about risks [35].
In our study, 3.8% opted for implant supported prosthesis. A
substantial body of evidence shows patients report greater satisfaction with the stability and retention with their implant supported-
prostheses which, in turn, appears to contribute to greater
satisfaction with comfort and ability to chew different foods. Esthetics
have been reported with implant supported prosthesis[36].
Retraction cords can be used while taking the impression for ceramic
restorations for the crown to provide improved aesthetic
results without any marginal discrepancy [36-40]. The dimensions
of the teeth in edentulous patients can be determined using extraoral
and intraoral factors [41]. Studies have shown that denture
patients may be willing to pay the additional treatment cost for
implants if payment options are more favorable [42]. dental insurance
systems that facilitate access to dental treatment have a
positive influence on attitudes and the motivation for utilization
of dental services [43].
In our study, 42% of the participants had implant supported dentures
in both arches. De Bruyn found that 90% of the patients
treated with fixed implant prostheses in the maxilla or mandible
were willing to undergo the same treatment again [44].
In our study, 42% preferred implant supported prosthesis for the
mandible alone. This could be because patient's objective chewing
efficiency is significantly increased when the lower conventional
denture is stabilised by means of implants [10]. More recent evidence
demonstrates that patients with mandibular implant-supported
overdentures are more likely to positively modify their diet
than patients with conventional dentures. implant-retained mandibular
overdentures are a very reliable alternative and especially
for those who have difficulties adapting to conventional dentures
[45].
In our study, only 14% preferred an implant supported prosthesis
for the upper arch alone. De Bruyn et al. treated patients with
fixed implant-supported prostheses in the maxilla and found significant
improvements in esthetics, eating-comfort, phonetics,
and overall satisfaction [44]. Another study, contradictory to ours,
by Jemt reported a frequent occurrence of speech problems associated
with fixed maxillary implant prostheses applied in the
resorbed maxilla [46]. An increased intermaxillary space because
of severe bone resorption was an indicator for recommending a
removable and not a fixed reconstruction [47].
In our study, for maxillary implant prosthesis 6 implants was the
most preferred (66%) while 4 implants were used in 34% and for
the mandible 4 implants (81%)was most commonly placed. There
is sound evidence that two-implant-retained mandibular overdentures
result in better patient-based outcomes than CD [48]. When
patients are given the opportunity to compare, they tend to prefer
a removable mandibular prosthesis fully supported by four implants
over an overdenture that is retained by two implants. It has
already been suggested that the much lower levels of satisfaction
that characterize conventional mandibular dentures are probably
due almost entirely to the poor bearing properties of the soft tissues
[49]. Whilst they are certainly more expensive, the use of just
two implants can keep the initial cost to a minimum.
In our study, the percentage distribution shows 35.7% had cement
retained prosthesis, 42.9% had screw retained FMR, 14.3%
had over dentures and 7.1% had hybrid prosthesis. One of the
complications that arise with screw retained prosthesis is screw
loosening [50]. However , sand blasting and diamond abrading of
the surface can improve the bond strength of luting agents under
masticatory load [51]. Implants supported overdentures offer
many of the benefits of retained roots while avoiding a number
of the liabilities from those roots [52]. Implant-supported hybrid
prosthesis is an acrylic resin complete fixed dental prosthesis and
supported by implants might be a solution in extreme cases that
the need of the restoration for esthetics, function, lip support, and speech [53].
The most common post-insertion complication is denture stomatitis
and the elimination of denture faults, control of denture
plaque and discontinuous denture wearing are sufficient treatment.
The routine use of antiseptic or antimycotic drugs seems
unnecessary [54, 55]. Topical application of local anaesthetic
agents and anti inflammatory gels can be advised [56].
Treatment decisions for edentulousness and the motives underlying
patients’ preferences are expected to vary greatly among individuals.
This clubbed with clinical judgement will reward promising
outcomes that can satisfy both the doctor and the patient.
Across all age groups and gender, the present study showed that a
conventional complete Denture was the obvious choice of treatment
for both the maxilla and mandible in edentulous patients.
Psychological factors are considered to be extremely important
in the acceptance of and adaptation to dentures [57], and many
patients develop the skills required to overcome limitations of
dentures and learn to accept these limitations with time [58]. This
can aid in patient counselling while presenting them with alternate
paths of treatment and identifying the best option for themselves.
Our institution is passionate about high quality evidence based
research and has excelled in various fields [59-69].
Small sample size, geographic isolation, socio economic factors,
systemic complications contribute to the limitations of the study.
The bone height and width for the placement of the implant and
need for bone augmentation have not been assessed among the
patients.
Conclusion
Within the limitations of the study, it can be concluded that a
significant association is seen between age and patients opting for
full mouth rehabilitation with implant prosthesis. There is however,
no significant association between gender and patients opting
for full mouth rehabilitation. Socioeconomic status and awareness
were the most common factors influencing decision making.
Author’s Contribution
Author 1 (Jerusha Santa Packyanathan) carried out the retrospective
study by collecting data and drafted the manuscript after performing
the necessary statistical analysis. Author 2 (Padma Ariga)
aided in the conception of the topic, participated in the study
design, statistical analysis, supervised in the preparation of the
manuscript and author 3 (Ganesh Jeevanandan) helped in study
design and coordinated in developing the manuscript. All the authors
have equally contributed in developing the manuscript.
Acknowledgement
The authors would like to acknowledge the support rendered by
the management and Department of Prosthodontics and information
technology of saveetha dental college and hospital .
References
- Chiapasco M, Zaniboni M, Boisco M. Augmentation procedures for the rehabilitation of deficient edentulous ridges with oral implants. Clin. Oral Implants Res. 2006 Oct;17(S2):136-59.
- Basha FY, Ganapathy D, Venugopalan S. Oral hygiene status among pregnant women. Res J Pharm Technol. 2018;11(7):3099-102. a name="ref3">
- Wehmeyer MM, Corwin CL, Guthmiller JM, Lee JY. The impact of oral
- Heasman L, Stacey F, Preshaw PM, McCracken GI, Hepburn S, Heasman PA. The effect of smoking on periodontal treatment response: a review of clinical evidence. J. Clin. Periodontol. 2006 Apr;33(4):241-53.
- Tyson KW. Physical factors in retention of complete upper dentures. J. Prosthet. Dent. 1967 Aug 1;18(2):90-7.
- “Eric” Hamrick JF. Horizontal Alveolar Ridge Augmentation Using Titanium Mesh and Particulate Bone Graft for the Treatment of Alveolar Ridge Defects. Horizontal Alveolar Ridge Augmentation in Implant Dentistry: A Surgical Manual. 2016 Jan 4:107-19.
- Ashok V, Nallaswamy D, Benazir Begum S, Nesappan T. Lip Bumper Prosthesis for an Acromegaly Patient: A Clinical Report. J Indian Prosthodont Soc. 2014 Dec;14(Suppl 1):279-82.Pubmed PMID: 26199531.
- Bencharit S, Schardt-Sacco D, Border MB, Barbaro CP. Full mouth rehabilitation with implant-supported prostheses for severe periodontitis: a case report. Open Dent. J. 2010;4:165.
- Rad AS, Siadat H, Monzavi A, Mangoli AA. Full mouth rehabilitation of a hypohidrotic ectodermal dysplasia patient with dental implants: a clinical report. J. Prosthodont. 2007 May;16(3):209-13.
- Thomason JM, Feine J, Exley C, Moynihan P, Müller F, Naert I, et al. Mandibular two implant-supported overdentures as the first choice standard of care for edentulous patients--the York Consensus Statement. Br Dent J. 2009 Aug 22;207(4):185-6.Pubmed PMID: 19696851.
- Hafeez N. Accessory foramen in the middle cranial fossa. Res. J. Pharm. Technol. 2016;9(11):1880-2.
- Krishnan RP, Ramani P, Sherlin HJ, Sukumaran G, Ramasubramanian A, Jayaraj G, et al. Surgical Specimen Handover from Operation Theater to Laboratory: A Survey. Ann Maxillofac Surg. 2018 Jul-Dec;8(2):234-238. Pubmed PMID: 30693238.
- Somasundaram S, Ravi K, Rajapandian K, Gurunathan D. Fluoride Content of Bottled Drinking Water in Chennai, Tamilnadu. J Clin Diagn Res. 2015 Oct;9(10):ZC32-4.Pubmed PMID: 26557612.
- Felicita AS. Orthodontic extrusion of Ellis Class VIII fracture of maxillary lateral incisor - The sling shot method. Saudi Dent J. 2018 Jul;30(3):265- 269.Pubmed PMID: 29942113.
- Kumar S, Rahman R. Knowledge, awareness, and practices regarding biomedical waste management among undergraduate dental students. Asian J. Pharm. Clin. Res. 2017;10(8):341.
- Gurunathan D, Shanmugaavel AK. Dental neglect among children in Chennai. J Indian Soc Pedod Prev Dent. 2016 Oct 1;34(4):364.
- Sneha S. Knowledge and awareness regarding antibiotic prophylaxis for infective endocarditis among undergraduate dental students. Asian J. Pharm. Clin. Res. 2016 Oct 1:154-9.
- . Dhinesh B, Lalvani JI, Parthasarathy M, Annamalai K. An assessment on performance, emission and combustion characteristics of single cylinder diesel engine powered by Cymbopogon flexuosus biofuel. Energy Convers. Manag. 2016 Jun 1;117:466-74.
- . Choudhari S, Thenmozhi MS. Occurrence and Importance of Posterior Condylar Foramen. Res J Pharm Technol. 2016;9(8):11-43.
- Paramasivam A, Vijayashree Priyadharsini J, Raghunandhakumar S. N6- adenosine methylation (m6A): a promising new molecular target in hypertension and cardiovascular diseases. Hypertens Res. 2020 Feb;43(2):153- 154.Pubmed PMID: 31578458.
- Wu F, Zhu J, Li G, Wang J, Veeraraghavan VP, Krishna Mohan S, et al. Biologically synthesized green gold nanoparticles from Siberian ginseng induce growth-inhibitory effect on melanoma cells (B16). Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3297-3305.Pubmed PMID: 31379212.
- Palati S, Ramani P, Shrelin HJ, Sukumaran G, Ramasubramanian A, Don KR, et al. Knowledge, Attitude and practice survey on the perspective of oral lesions and dental health in geriatric patients residing in old age homes. Indian J Dent Res. 2020 Jan-Feb;31(1):22-25.Pubmed PMID: 32246676.
- Saravanan M, Arokiyaraj S, Lakshmi T, Pugazhendhi A. Synthesis of silver nanoparticles from Phenerochaete chrysosporium (MTCC-787) and their antibacterial activity against human pathogenic bacteria. Microb Pathog. 2018 Apr;117:68-72.Pubmed PMID: 29427709.
- Govindaraju L, Gurunathan D. Effectiveness of Chewable Tooth Brush in Children-A Prospective Clinical Study. J Clin Diagn Res. 2017 Mar;11(3):ZC31-ZC34.Pubmed PMID: 28511505.
- Vijayakumar Jain S, Muthusekhar MR, Baig MF, Senthilnathan P, Loganathan S, Abdul Wahab PU, et al. Evaluation of Three-Dimensional Changes in Pharyngeal Airway Following Isolated Lefort One Osteotomy for the Correction of Vertical Maxillary Excess: A Prospective Study. J Maxillofac Oral Surg. 2019 Mar;18(1):139-146.Pubmed PMID: 30728705.
- de Castellucci Barbosa L, Ferreira MR, de Carvalho Calabrich CF, Viana AC, De Lemos MC, Lauria RA. Edentulous patients’ knowledge of dental hygiene and care of prostheses. Gerodontology. 2008 Jun;25(2):99-106.
- Douglass CW, Shih A, Ostry L. Will there be a need for complete dentures in the United States in 2020? J Prosthet Dent. 2002 Jan;87(1):5-8.Pubmed PMID: 11807476.
- Adams C, Slack-Smith LM, Larson A, O'Grady MJ. Edentulism and associated factors in people 60 years and over from urban, rural and remote Western Australia. Aust Dent J. 2003 Mar;48(1):10-4.Pubmed PMID: 14640151.
- Javed F, Klingspor L, Sundin U, Altamash M, Klinge B, Engström PE. Periodontal conditions, oral Candida albicans and salivary proteins in type 2 diabetic subjects with emphasis on gender. BMC Oral Health. 2009 May 12;9:12.Pubmed PMID: 19435501.
- Jyothi S, Robin PK, Ganapathy D. Periodontal health status of three different groups wearing temporary partial denture. Res J Pharm Technol. 2017;10(12):4339-42.
- Venugopalan S, Ariga P, Aggarwal P, Viswanath A. Case Report: Magnetically retained silicone facial prosthesis. Niger. J. Clin. Pract. 2014 Mar 27;17(2):260-4.
- Srisilapanan P, Korwanich N, Sheiham A. Assessing prosthodontic dental treatment needs in older adults in Thailand: normative vs. sociodental approaches. Spec Care Dentist. 2003 Jul-Aug;23(4):131-4.Pubmed PMID: 14765891.
- Kaptein ML, Hoogstraten J, de Putter C, de Lange GL, Blijdorp PA. Dental implants in the atrophic maxilla: measurements of patients' satisfaction and treatment experience. Clin Oral Implants Res. 1998 Oct;9(5):321-6.Pubmed PMID: 9835811.
- Liddelow GJ, Henry PJ. A prospective study of immediately loaded single implant-retained mandibular overdentures: preliminary one-year results. J Prosthet Dent. 2007 Jun;97(6 Suppl):S126-37.Pubmed PMID: 17618927.
- Walton JN, MacEntee MI. Choosing or refusing oral implants: A prospective study of edentulous volunteers for a clinical trial. J Prosthet Dent . 2006 Nov 1;96(5):353.
- Ashok V, Suvitha S. Awareness of all ceramic restoration in rural population. Res J Pharm Technol. 2016;9(10):1691-3.
- Kannan A, Venugopalan S. A systematic review on the effect of use of impregnated retraction cords on gingiva. Res J Pharm Technol. 2018;11(5):2121-6.
- Ranganathan H, Ganapathy DM, Jain AR. Cervical and Incisal Marginal Discrepancy in Ceramic Laminate Veneering Materials: A SEM Analysis. Contemp Clin Dent. 2017 Apr-Jun;8(2):272-278.Pubmed PMID: 28839415.
- Ganapathy D, Sathyamoorthy A, Ranganathan H, Murthykumar K. Effect of Resin Bonded Luting Agents Influencing Marginal Discrepancy in All Ceramic Complete Veneer Crowns. J Clin Diagn Res. 2016 Dec;10(12):ZC67- ZC70.Pubmed PMID: 28209008.
- Duraisamy R, Krishnan CS, Ramasubramanian H, Sampathkumar J, Mariappan S, Navarasampatti Sivaprakasam A. Compatibility of Nonoriginal Abutments With Implants: Evaluation of Microgap at the Implant-Abutment Interface, With Original and Nonoriginal Abutments. Implant Dent. 2019 Jun;28(3):289-295.Pubmed PMID: 31124826.
- Jain AR, Nallaswamy D, Ariga P, Ganapathy DM. Determination of correlation of width of maxillary anterior teeth using extraoral and intraoral factors in Indian population: A systematic review. World J Dent. 2018 Jan;9(1):68- 75.
- . Esfandiari S, Lund JP, Penrod JR, Savard A, Thomason JM, Feine JS. Implant overdentures for edentulous elders: study of patient preference. Gerodontology. 2009 Mar;26(1):3-10.Pubmed PMID: 18498362.
- Narby B, Kronström M, Söderfeldt B, Palmqvist S. Prosthodontics and the patient. Part 2: Need becoming demand, demand becoming utilization. Int J Prosthodont. 2007 Mar-Apr;20(2):183-9.Pubmed PMID: 17455442.
- de Bruyn H, Collaert B, Lindén U, Björn AL. Patient's opinion and treatment outcome of fixed rehabilitation on Brånemark implants. A 3-year follow-up study in private dental practices. Clin Oral Implants Res. 1997 Aug;8(4):265-71.Pubmed PMID: 9586472.
- Feine JS, Carlsson GE. Implant overdentures the standard of care for edentulous patients. New York. 2003.
- Jemt T, Lindén B, Lekholm U. Failures and complications in 127 consecutively placed fixed partial prostheses supported by Brånemark implants: from prosthetic treatment to first annual checkup. Int J Oral Maxillofac Implants. 1992 Spring;7(1):303.Pubmed PMID: 1398822.
- Zitzmann NU, Marinello CP. Treatment outcomes of fixed or removable implant-supported prostheses in the edentulous maxilla. Part I: patients’ assessments. J. Prosthet. Dent.. 2000 Apr 1;83(4):424-33.
- Emami E, Heydecke G, Rompré PH, de Grandmont P, Feine JS. Impact of implant support for mandibular dentures on satisfaction, oral and general health-related quality of life: a meta-analysis of randomized-controlled trials. Clin Oral Implants Res. 2009 Jun;20(6):533-44.Pubmed PMID: 19515032.
- Boerrigter EM, Stegenga B, Raghoebar GM, Boering G. Patient satisfaction and chewing ability with implant-retained mandibular overdentures: a comparison with new complete dentures with or without preprosthetic surgery. J Oral Maxillofac Surg. 1995 Oct 1;53(10):1167-73.
- Ganapathy DM, Kannan A, Venugopalan S. Effect of coated surfaces influencing screw loosening in implants: A systematic review and meta-analysis. World J. Dent. 2017 Nov;8(6):496-502.
- Ajay R, Suma K, Ali SA, Kumar Sivakumar JS, Rakshagan V, Devaki V, et al. Effect of Surface Modifications on the Retention of Cement-retained Implant Crowns under Fatigue Loads: An In vitro Study. J Pharm Bioallied Sci. 2017 Nov;9(Suppl 1):S154-S160.Pubmed PMID: 29284956.
- Adell R, Lekholm U, Rockler BR, Brånemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg. 1981 Jan 1;10(6):387-416.
- Egilmez F, Ergun G, Cekic-Nagas I, Bozkaya S. Implant-supported hybrid prosthesis: Conventional treatment method for borderline cases. Eur J Dent. 2015 Jul-Sep;9(3):442-448.Pubmed PMID: 26430378.
- Selvan SR, Ganapathy D. Efficacy of fifth generation cephalosporins against methicillin-resistant Staphylococcus aureus-A review. Res J Pharm Technol. 2016;9(10):1815-8.
- Vijayalakshmi B, Ganapathy D. Medical management of cellulitis. Res J Pharm Technol. 2016;9(11):2067-70.
- Subasree S, Murthykumar K. Effect of aloe vera in oral health-A review. Res J Pharm Technol. 2016;9(5):609-12.
- Carlsson GE. Clinical morbidity and sequelae of treatment with complete dentures. J. Prosthet. Dent. 1998 Jan 1;79(1):17-23.
- Allen PF, McMillan AS. A review of the functional and psychosocial outcomes of edentulousness treated with complete replacement dentures. J Can Dent Assoc. 2003 Nov;69(10):662.Pubmed PMID: 14611716.
- Vijayashree Priyadharsini J. In silico validation of the non-antibiotic drugs acetaminophen and ibuprofen as antibacterial agents against red complex pathogens. J Periodontol. 2019 Dec;90(12):1441-1448.Pubmed PMID: 31257588.
- Pc J, Marimuthu T, Devadoss P, Kumar SM. Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross sectional study. Clin Implant Dent Relat Res. 2018 Apr 6;20(4):531-4.
- Ramesh A, Varghese S, Jayakumar ND, Malaiappan S. Comparative estimation of sulfiredoxin levels between chronic periodontitis and healthy patients - A case-control study. J Periodontol. 2018 Oct;89(10):1241-1248.Pubmed PMID: 30044495.
- Ramadurai N, Gurunathan D, Samuel AV, Subramanian E, Rodrigues SJ. Effectiveness of 2% Articaine as an anesthetic agent in children: randomized controlled trial. Clin Oral Investig. 2019 Sep;23(9):3543-50.
- Sridharan G, Ramani P, Patankar S, Vijayaraghavan R. Evaluation of salivary metabolomics in oral leukoplakia and oral squamous cell carcinoma. J Oral Pathol Med. 2019 Apr;48(4):299-306.
- Ezhilarasan D, Apoorva VS, Ashok Vardhan N. Syzygium cumini extract induced reactive oxygen species-mediated apoptosis in human oral squamous carcinoma cells. J Oral Pathol Med. 2019 Feb;48(2):115-121.Pubmed PMID: 30451321.
- Mathew MG, Samuel SR, Soni AJ, Roopa KB. Evaluation of adhesion of Streptococcus mutans, plaque accumulation on zirconia and stainless steel crowns, and surrounding gingival inflammation in primary molars: randomized controlled trial. Clin Oral Investig. 2020 Sep;24(9):1-6.Pubmed PMID: 31955271.
- Samuel SR. Can 5-year-olds sensibly self-report the impact of developmental enamel defects on their quality of life? Int J Paediatr Dent. 2021 Mar;31(2):285-286.Pubmed PMID: 32416620.
- . R H, Ramani P, Ramanathan A, R JM, S G, Ramasubramanian A, et al. CYP2 C9 polymorphism among patients with oral squamous cell carcinoma and its role in altering the metabolism of benzo[a]pyrene. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Sep;130(3):306-312.Pubmed PMID: 32773350.
- Chandrasekar R, Chandrasekhar S, Sundari KKS, Ravi P. Development and validation of a formula for objective assessment of cervical vertebral bone age. Prog Orthod. 2020 Oct 12;21(1):38.Pubmed PMID: 33043408.
- Vijayashree Priyadharsini J, Smiline Girija AS, Paramasivam A. In silico analysis of virulence genes in an emerging dental pathogen A. baumannii and related species. Arch Oral Biol. 2018 Oct;94:93-98.Pubmed PMID: 30015217.