CAD/CAM System Vs. Laser Milling Zirconia For Fixed Restoration Construction; Narrative Review
Ali Fahmy1, Raafat Tammam2*
1 Professor of Fixed prosthodontics faculty of Dentistry, Deraya University, New Minya, Egypt.
2 Associate Professor Of Fixed Prosthodontics, Faculty Of Dentistry, Assiut University, Deraya University, Egypt.
*Corresponding Author
Raafat Abd El-Rhman Tammam Attia,
Associate Professor & Consultant of Fixed Prosthodontics, Implantology And Cosmotic Dentistry, Faculty Of Dentistry, Assiut University, Egypt.
Tel: 01006787624/0882350112
Fax: 0882350113
E-mail: raafat@aun.edu.eg
Received: October 31, 2021; Accepted: November 28, 2021; Published: December 09, 2021
Citation: Ali Fahmy, Raafat Tammam. CAD/CAM System Vs. Laser Milling Zirconia For Fixed Restoration Construction; Narrative Review. Int J Dentistry Oral Sci. 2021;8(12):5207-5211. doi: dx.doi.org/10.19070/2377-8075-210001044
Copyright: Raafat Abd El-Rhman Tammam Attia©2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
The aim of This review article compares the use of a computer-aided design (CAD) system, and laser milling in fabricating dental prostheses made of zirconia ceramics (TZP).Since Land made the first all-ceramic crown with low-strength feldspar porcelain in 1903 [1], dental all-ceramic restoration materials' mechanical and aesthetic properties have been significantly evolved. Therefore, In dental clinics, these are commonly utilized. Many ways for fabricating all-ceramic dental restorations have recently been developed [2]. All-ceramic materials, on the other hand, are fragile and difficult to work with due to their high hardness and low fracture toughness. Zirconia ceramics are utilized in dental restorations because of their strong mechanical qualities, which allow them to be employed as entire ceramic restorations for long-span bridges. Milling fully sintered Zirconia might be difficult because of its extreme hardness. Instead, a CAD/CAM system is used to grind a partially sintered zirconia block, which is then sintered in a furnace. Sintering results in a linear shrinkage of 15% to 30%. [3]. For the softer partially sintered stone, milling efficiency is improved. To avoid restorative unfitnesscaused by sintering shrinkage, scanning operation, and milling [4]., laser machining of high-hardness Zirconia is employed. In dentistry, a variety of lasers are now operational.
2.Introduction
3.Materials and Methods
3.Results
4.Discussion
5.Conclusion
5.References
Keywords
Dental Constructions; Laser Milling; Zirconia' CAD-CAM; Dentistry.
Introduction
In the last 30 years, the production technology for dental restoration
has developed rapidly. Digitalization, simulation, the use
of additive technologies, and lasers are the four primary themes
in the process. This simulation was the first, and because to advances
in computer technology, it has progressed quickly from
mathematical calculations and analysis to 3D modeling and visualization.
As a result, Computer-Aided Engineering (CAE) was
created to generate the best-designed dental repair using the most
technologically advanced technology. Recently, laser milling has
been used to overcome CAD/CAM problems during the manufacturing
process of zirconia ceramic restorations. The focus of
this article will be on CAD/CAM systems and laser milling to
manufacture dental restoration made of zirconium. [5]
Yttria stabilized zircon
TZP ceramic has excellent mechanical properties at roomtemperature;
therefore, it is considered the best choice for ceramic
restorations [6]. Depending on the temperature, unalloyed Zirconia
takes one of three crystalline forms: monoclinic, tetragonal,
or cubic. Among the three crystal types, tetragonal Zirconia has
the best mechanical characteristics. Various oxides (such as CaO,
MgO, Y2O3, or CeO2) are employed to achieve a stable tetragonal
phase in Zirconia at room temperature [7, 8]. To assess phase
stability, transformability, and mechanical properties, these oxides
should be introduced in an appropriate amount [9]. Because of
its comparatively tiny grain size and four-directional monoclinic
phase transition, the 3 mol percent yttria-stabilized tetragonal Zirconia
polycrystalline (3Y-TZP) possesses exceptional mechanical
properties.
This leads to a 4 – 5% increase in volume [8, 10], inhibiting crack
propagation by the closure of the crack tip [9]. To circumvent the
issue of chipping of porcelain layers put over Zirconia, monolithic
(full-profile) (Y-TZP) restorations have recently been developed
[11-13]. Because of its high strength of over 1000 MPa and
outstanding fracture toughness of 4 to 5 MPa, Y-TZP is performing
well in dental ceramics.
The increased translucency of the new zirconia materials was obtained
through microstructural alterations such as alumina reduction,
density increase, grain size reduction, addition of Cubic Zirconia,
and reduction of impurities and structural defects.[14, 15].
The first attempt at obtaining translucent ceramic materials was
done by increasing the grain size during sintering [16]. Larger
grains result in fewer grain boundaries, which reduces light scattering;
nevertheless, larger crystal grains degrade both the mechanical
characteristics and tetragonal phase stability of Y-TZP;
hence, increasing the grain size of Zirconia does not result in increased
translucency.
Another technique to make Y-TZP more translucent is to reduce
the grain scale. However, before reaching a threshold number
that mitigates the so-called birefringence phenomena, the crystal
grain size must be lowered. The high amount of tetragonal crystal
phase (> 90%) in Y-TZP causes birefringence, which is a type
of crystal with different refractive indices based on its crystallographic
orientation in the microstructure. Significant light scattering
is caused by the anisotropic behavior associated with refractive
index variance.. Cubic Zirconia is used to counteract these
scattering effects due to its optically isotropic properties, which
increases translucency [15, 17].
Ultra-translucent Zirconia is drawing attracting much attention.
Because they have a good aesthetic look. Due of the enhanced
cubic-zirconia content, the high translucency came at the expense
of strength and transformation toughening ability. To overcome
these issues, glass will be infiltrated on the surface of ultra-translucent
Zirconia. (5Y-PSZ)[18].
CAD/CAM system
CAD/CAM dentistry can provide various dental restorations, including
crowns, veneers, inlays, fixed bridges, dental implant restorations,
and orthodontic appliances.[19]
CAD/CAM systems are divided into two categories: chair end
and laboratory.
a-Lab – CAD/CAM for dental laboratories [20]
b-Chairside CAD/CAM Restorations [21]
As a result of digitalization, the first Computer-Aided Design
(CAD) – Computer-Aided Manufacturing (CAM) systems were
developed in the 1970s [22, 23]. Dr. Duret was the one who pioneered
the use of CAD-CAM in dentistry. For a prepared abutment
tooth, an optical impression was taken. After that, a crown
was made with a numeric control machine. In the year 1971, he
accomplished this feat in the realm of dentistry. [24]. After that,
T Miyazaki and his colleagues worked on the Sopha system and
attempted to introduce it, but the system was not widely accepted
[25]. Mormann introduced a commercial designed CAD CAM
system ( CEREC)in 1985 [26]. After obtaining a digital impression
from an intraoral camera, he made an inlay from ceramic
blocks. This system has been successfully used to manufacture
crowns, inlays, onlays, etc., worldwide. Dr. Anderssondeveloped
the Procera system in the mid-1980s and replaced nickel-chromium
alloys on titanium for machining [27].
CEREC2 was introduced by Siemens in 1994. Inlays, onlays, veneers,
crowns, and copings can all be made with this method.
CEREC's third version, which can create inlays, veneers, partial
and complete crowns, copings, and virtually automatic occlusal
corrections, is now in use. Sirona introduced this technology in
2005, which is essentially an enhanced version of Sirona's CEREC
3 system, which was first introduced in 2000 but only worked on
two-dimensional principles and couldn't make anatomic occlusal
corrections.[28].
The geometry of the parts to be produced is defined in the first
CAD stage. The information used for production will be merged
in the second stage, the CAM stage, and the main production
machine will be controlled.[29-31].
Three practical components make up CAD-CAM systems: 1) a
scanner that translates geometry into digital data that a computer
can process; 2) software that analyzes the scanned data and provides
a data set that a fabrication system can read; and 3) fabrication
equipment that takes the data set and fabricates the reconstruction.[
32, 33].
The data for the 3D model is gathered through indirect scanning
of the plaster model during the initial stage of CAD development.
The dentist (taking an impression) and the dental technician
(producing a dental construction) undertake the initial procedures
by hand in this situation (pouring the plaster model). After that,
the plaster model is scanned utilizing either contact [34, 35] or
reduced contact scanning. [36, 37].
Specialized software builds a virtual 3D model from scanned data,
which is subsequently sent to the CAM machine for manufacture.
As a result, the actual dental structure or the polymer casting
model can be machined using stereolithography (3D printing)[38,
39].
In the next stage of CAD development, data can be obtained
by directly scanning the prosthetic area in the patient's mouth.
This stage is the most recent result.Introduce an intraoral scanner.
Many software packages are available for designing crowns,
bridges, and partial denture frames in less than 20 minutes [30].
In comparing CAD-CAM restorations with the conventional one,
CAD-CAM offers quick and easy fabrication of ideal restoration-
Intraoral Scanning requires less time than a traditional impression,
and patients can obtain their restorations in one appointment using
the chairside technology. Despite the high quality of these
restorations, certain flaws exist, related to;
1) The precise internal fit of the restoration depends on the size
of the available tool.
2) Many materials are wasted because sometimes, about 90% of
the initial block can be removed [30].
3) Wearing of the milling tools.
4) Ceramic is a brittle material; Microcracks can appear on its surface due to the processing [32].
In addition to these limitations, cost remains a significant issue.
Vita Mark II or Dicor (Dentsply). Some machinable glass-ceramics
were employed in early dental CAD/CAM restorations. These
monochromatic ceramics feature great aesthetics, biocompatibility,
color consistency, low heat conductivity, and wear resistance
while being monochromatic [39]. They're used to make inlays,
veneers, and crowns. Dicor and Vita Mark II are not suggested
for posterior crowns due to their poor mechanical qualities. As a
result, dental restorative materials made of alumina and zirconia
are becoming more popular [40-44]. Presenting alumina or zirconia
blocks machined using CAD/CAM technology and then
veneered with ceramics meets the requirement for all-ceramic
posterior crowns and fixed partial dentures.
CAD/CAM technology is required to make these ceramic agents
cost-effective. Sadoun and Degrange [46], for example, first mentioned
In-Ceram 1 [45], which has been demonstrated to have
good flexural strength and clinical efficacy. Traditional pottery
restoration, on the other hand, can take up to 14 hours to complete.[
47, 48].
Grinding fully sintered zirconia material is difficult, and a single
unit takes three hours to accomplish. Although milling copings
from pre-sintered alumina or zirconia blocks takes 20 minutes,
it cuts glass infiltration time from 4 hours to 40 minutes, reduces
tool loading and wear, and improves accuracy.
Under stress, the stable tetragonal phase can be changed to the
monoclinic phase with a 3-4% volume increase. As a result of
the dimension transition, compressive stresses are formed, which
restrict fracture growth. This is referred to as "transformation
toughening," and it is this process that lends Zirconia its "smart
ceramic" label. To offer aesthetics and reduce wear of the opposing
teeth, zirconia copings are laminated with low fusing porcelain
[49, 50]
Laser milling
As mentioned before, two different types of zirconia blocks can
be used in CAD/CAM applications. The first one is to use fully
sintered compact blocks for CAD/CAM manufacturing. Because
the procedure does not require shrinkage, this application has a
better fit, but it has a disadvantage in terms of machinability due
to greater milling tool wear. Furthermore, the creation of microcracks
in the material during the grinding process may diminish
the restoration's mechanical endurance. The second application
employs partially sintered and green blocks for CAD/CAM
manufacture, followed by post-sintering to achieve a strong final
product [20]. The advantage of this application is that it is easy
to machine without causing too much wear or material chipping
on the tool. However, since a large amount of shrinkage occurs
during the post-sintering process, it is necessary to compensate
for the suitability of the frame by adjusting the size of the CAD
program involving the frame [51].
In order to overcome this problem, laser milling is the best solution.
Laser milling (LM) is a layer manufacturing technique in which
material is removed by a laser beam using an ablation device. It
has obvious advantages over traditional milling, such as an unrestricted
material variety, direct use of computer-aided design
structure data, high geometric flexibility, and non-contact tools.
The ablation depth in LM, unlike mechanical milling and mechanical
incision, is determined by process factors such as laser power,
scanning speed, pulse duration, and pulse frequency. These parameters
are chosen at the start of the process as an input parameter
[52].
Laser machine
The structure diagram of the laser system and laser processing
system used in the research conducted by Peixin Hu et al. [53] is
shown in Figure 1.
Laser manufacturing offers numerous benefits, including low tool
wear, superior environmental safety, high processing accuracy
and performance, and low noise. Furthermore, because the laser
beam's diameter is at least ten times smaller than the diameter of
a traditional milling bur, it can mill crowns with high-resolution
details.
Ahmed El Gamal and colleagues published a study in 2015 that
used 10 W carbon dioxide lasers and neodymium-doped yttrium
aluminum titanium ore (Nd: YAP) lasers to modify the surface of
two types of ceramics (IPSe.max CAD) and (IPS e.maxZirCADs)
[54]. They discovered that CO2 and Nd: YAP lasers can change
ceramics and increase bonding strength without using any chemicals.
Peixin Hu et al. [53] conducted a study to use ultrashort pulse
laser (USPL) for making dental restorations from dental ceramic
blocks. The results indicated that the processing method could
reduce manufacturing costs and improve milling efficiency and
precision.
A study was conducted in 2018 to compare the CAD/CAM milling system with a three-axis and five-axis Nd: YVO4 fiber semiconductor
laser system for milling zirconia prostheses, and they
discovered that the five-axis laser milling group produced the
most satisfactory manufacturing results; the roundness of edges
and internal shapes is almost perfect. The three-axis laser group
and the conventional group, on the other hand, have no discernible
differences.[55]
Ohkuma K et al. [56] developed a laser milling machine for direct
milling of fully sintered zirconia blocks. They began with a
three-axis laser milling machine for zirconia prostheses, but due
to its processing limitation (milling the sample in the prosthesis'
longitudinal direction), they developed and built a five-axis milling
machine that can produce zirconia prostheses suitable for clinical
use. The number of axes and the movement of the machine tool
are the key differences between a five-axis milling machine and
a three-axis milling machine. When compared to three-axis laser
milling and traditional heating specimens, the research findings
reveal that a zirconia crown made from a fully sintered zirconia
block utilizing a five-axis laser milling system has exceptional dimensions
and shape accuracy.
Compared with other methods, the use of laser processing ceramics
has many advantages. Laser processing is a non-contact
technology that can process many types of ceramics with high
precision and eliminates expensive processing costs. The nanosecond
Nd:YVO4 laser machine has successfully fabricated a coping
from fully sintered Y-TZP [57].
Nanosecond pulsed Nd: YAG lasers are suitable for precision machining
of a Y-TZP ceramic. However, it has been demonstrated
that the process is highly non-linear, with ceramics having a very
poor absorption rate before reaching a strength threshold, and
successful material removal only achievable above this threshold.
Preheating with earlier laser pulses can change this threshold, dramatically
improving the process's performance.[58]
Conclusion
The advent of computer-aided manufacturing technologies and
subsequent developments have revolutionized dentistry's standard
workflow, and practitioners are rapidly moving from traditional
to digital dentistry. As a result, intra-oral scanners have become
a standard device in dental clinics, despite their high cost.
One of the primary motivations for this digital transition is to
assure consistent manufacturing quality while reducing chair time,
as a fully digital workflow promises. The current state of dental
CAD/CAM systems and laser milling, particularly in the production
of zirconia ceramic crowns and bridge restorations, is discussed
in this article.
In the past ten years, dental ceramics and processing technology
have undergone significant changes, most of which are identified
with new microstructures and processing methods (CAD-CAM
and laser milling).
Due to the main disadvantage of CAD-CAM SYSTEM, the milling
bur wear that affects the marginal fit and internal fit of the
crown so need frequent changing the milling bur this confirmed
by a recent study to change milling burs at a proper frequency tomaintain
the accuracy of fit for CAD/CAM fabrication of dental
metal prostheses. Periodicchanges in milling burs were required
to achieve the quality of fit and predictable outcomesfor dental
CAD/CAM prostheses. Moreover, improved durability of cutting
edges in milling burs will reduce the fabrication costs for dental
CAD/CAM prostheses with lowmachinable materials.[59]
Aesthetic multilayered restorations are more liable to pilling;
accordingly, using monolithic restorations is the ideal solution
Zirconium oxide ceramic (Y-TZP) materials processed by CADCAM
or laser are considered the ideal choice because they have a
high strength level of more than 1000 MPa and excellent fracture
toughness of 4 to 5 MPa, which are superior in dental ceramics
Performance. Compared with the traditional Y-TZP, the microstructure
of the Y-TZP of the complete prosthesis has been adjusted
to improve its translucency.
In the manufacture of zirconia dental restorations, subtractive
manufacturing has largely supplanted additive manufacturing,
however additive manufacturing is gaining traction as a prospective
alternative. The purpose of this in vitro study was to compare
the output of stereolithography (SLA) and milling while fabricating
monolithic zirconia crowns with a variety of finish line designs.
They concluded that by comparing the efficiency of SLA
and milling in fabricating monolithic zirconia crowns with various
finish lines, they could compare the fabrication accuracy and
margin quality of monolithic zirconia crowns with various finish
lines. According to the findings, both SLA and milling can make
monolithic zirconia crowns with comparable precision. On the
other hand, when any of the two techniques is used, knife-edged
crowns are prone to wide margin chippings.[60]
Based on the data obtained from this review article, we can conclude
that the laser milling system performs well in making zirconia
prostheses with precise dimensions and shapes and has higher
accuracy than the CAD/CAM system.
References
-
[1]. Kelly JR, Nishimura I, Campbell SD. Ceramics in dentistry: historical roots
and current perspectives. J Prosthet Dent. 1996 Jan;75(1):18-32. PubMed
PMID: 9005250.
[2]. Silva LHD, Lima E, Miranda RBP, Favero SS, Lohbauer U, Cesar PF. Dental ceramics: a review of new materials and processing methods. Braz Oral Res. 2017 Aug 28;31(suppl 1):e58. PubMed PMID: 28902238.
[3]. Beuer F, Aggstaller H, Edelhoff D, Gernet W, Sorensen J. Marginal and internal fits of fixed dental prostheses zirconia retainers. Dent Mater. 2009 Jan;25(1):94-102. PubMed PMID: 18620749.
[4]. Denry I, Holloway JA. Ceramics for dental applications: a review. Materials. 2010 Jan;3(1):351-68.
[5]. Irfan UB, Aslam K, Nadim R. A review on cad cam in dentistry. J Pak Dent Assoc. 2015; 24(3):112116.
[6]. Nettleship I, Stevens R. Tetragonal zirconia polycrystal (TZP)—a review. International journal of high technology ceramics. 1987 Jan 1;3(1):1-32.
[7]. Denry I, Kelly JR. State of the art of zirconia for dental applications. Dent Mater. 2008 Mar;24(3):299-307. PubMed PMID: 17659331.
[8]. Stawarczyk B, Ozcan M, Hallmann L, Ender A, Mehl A, Hämmerlet CH. The effect of zirconia sintering temperature on flexural strength, grain size, and contrast ratio. Clin Oral Investig. 2013 Jan;17(1):269-74. PubMed PMID: 22358379.
[9]. Shah K, Holloway JA, Denry IL. Effect of coloring with various metal oxides on the microstructure, color, and flexural strength of 3Y-TZP.J Biomed Mater Res B ApplBiomater. 2008 Nov;87(2):329-37. PubMed PMID: 18433010.
[10]. Chen YM, Smales RJ, Yip KH, Sung WJ. Translucency and biaxial flexural strength of four ceramic core materials. Dent Mater. 2008 Nov;24(11):1506- 11. PubMed PMID: 18440062.
[11]. Silva LHD, Lima E, Miranda RBP, Favero SS, Lohbauer U, Cesar PF. Dental ceramics: a review of new materials and processing methods. Braz Oral Res. 2017 Aug 28;31(suppl 1):e58. PubMed PMID: 28902238.
[12]. Marchack BW, Sato S, Marchack CB, White SN. Complete and partial contour zirconia designs for crowns and fixed dental prostheses: a clinical report. J Prosthet Dent. 2011 Sep;106(3):145-52. PubMed PMID: 21889000.
[13]. Schley JS, Heussen N, Reich S, Fischer J, Haselhuhn K, Wolfart S. Survival probability of zirconia-based fixed dental prostheses up to 5 yr: a systematic review of the literature. Eur J Oral Sci. 2010 Oct;118(5):443-50. PubMed PMID: 20831577.
[14]. Zhang H, Li Z, Kim B-N, Morita K, Yoshida H, Hiraga K et al. Effect of alumina dopant on transparency of tetragonal zirconia.J Nanomater. 2012. [15]. Zhang Y. Making yttria-stabilized tetragonal zirconia translucent. Dent Mater. 2014 Oct;30(10):1195-203. PubMed PMID: 25193781.
[16]. Cheng J, Agrawal D, Zhang Y, Roy R. Microwave sintering of transparent alumina. Mater Lett. 2002;56(4):587-92.
[17]. Klimke J, Trunec M, Krell A. Transparent tetragonal yttria-stabilized zirconia ceramics: influence of scattering caused by birefringence.J Am Ceram Soc. 2011;94(6):1850-8.
[18]. Mao L, Kaizer MR, Zhao M, Guo B, Song YF, Zhang Y. Graded Ultra- Translucent Zirconia (5Y-PSZ) for Strength and Functionalities. J Dent Res. 2018 Oct;97(11):1222-1228. PubMed PMID: 29694258.
[19]. Miyazaki T, Hotta Y. CAD/CAM systems available for the fabrication of crown and bridge restorations. Aust Dent J. 2011 Jun;56Suppl 1:97-106. PubMed PMID: 21564120.
[20]. Suttor D, Bunke K, Hoescheler S, Hauptmann H, Hertlein G. LAVA--the system for all-ceramic ZrO2 crown and bridge frameworks. Int J Comput Dent. 2001 Jul;4(3):195-206. PubMed PMID: 11862886.
[21]. Reiss B, Walther W. Clinical long-term results and 10-year Kaplan-Meier analysis of Cerec restorations. Int J Comput Dent. 2000 Jan;3(1):9-23. Pub- Med PMID: 11351392.
[22]. Bidra AS, Taylor TD, Agar JR. Computer-aided technology for fabricating complete dentures: systematic review of historical background, current status, and future perspectives. J Prosthet Dent. 2013 Jun;109(6):361-6. PubMed PMID: 23763779.
[23]. Chatham C, Spencer MH, Wood DJ, Johnson A. The introduction of digital dental technology into BDS curricula. Br Dent J. 2014 Dec 5;217(11):639- 42. PubMed PMID: 25476642.
[24]. Duret F, Preston JD. CAD/CAM imaging in dentistry.CurrOpin Dent. 1991 Apr;1(2):150-4. PubMed PMID: 1777659.
[25]. Miyazaki T, Hotta Y. CAD/CAM systems available for the fabrication of crown and bridge restorations. Aust Dent J. 2011 Jun;56Suppl 1:97-106. PubMed PMID: 21564120.
[26]. Mörmann WH, Brandestini M, Lutz F, Barbakow F. Chairside computeraided direct ceramic inlays. Quintessence Int. 1989 May;20(5):329-39. PubMed PMID: 2756089.
[27]. Miyazaki T, Hotta Y, Kunii J, Kuriyama S, Tamaki Y. A review of dental CAD/CAM: current status and future perspectives from 20 years of experience. Dent Mater J. 2009 Jan;28(1):44-56. PubMed PMID: 19280967.
[28]. Mörmann WH. The evolution of the CEREC system. J Am Dent Assoc. 2006 Sep;137 Suppl:7S-13S. PubMed PMID: 16950932.
[29]. Dikova T, Dzhendov D, Simov M, Katreva-Bozukova I, Angelova S, Pavlova D, et al. Modern trends in the development of the technologies for production of dental constructions. Journal of IMAB–Annual Proceeding Scientific Papers. 2015 Dec 30;21(4):974-81.
[30]. van Noort R. The future of dental devices is digital. Dent Mater. 2012 Jan;28(1):3-12. PubMed PMID: 22119539.
[31]. Strietzel R. Selective Laser Melting in Dentistry. Informatics inOral Medicine: Advanced Techniques in Clinical and Diagnostic Technologies. 2010; 111-125.
[32]. Torabi K, Farjood E, Hamedani S. Rapid Prototyping Technologies and their Applications in Prosthodontics, a Review of Literature. J Dent (Shiraz). 2015 Mar;16(1):1-9. PubMed PMID: 25759851.
[33]. Gaspar M, Weichert F. Integrated construction and simulation of tool paths for milling dental crowns and bridges. Computer-Aided Design. 2013 Oct 1;45(10):1170-81.
[34]. Dobrzanski LA. Digitization procedure of creating 3D model of dental bridgework reconstruction.Journal of Achievements in Materials and Manufacturing Engineering. 2012;55(2):469-76.
[35]. Shinya A, Yokoyama D. Finite element analysis for dental prosthetic design. IntechOpen; 2010 Aug 17.
[36]. Della Bona A, Borba M, Benetti P, Duan Y, Griggs JA. Three-dimensional finite element modelling of all-ceramic restorations based on micro-CT. J Dent. 2013 May;41(5):412-9. PubMed PMID: 23474359.
[37]. Almeida EO, Freitas JúniorAC,Rocha EP, Pessoa RS, Gupta N, Tovar N, et al. Critical Aspects for Mechanical Simulation in Dental Implantology, Finite ElementAnalysis- From Biomedical Applications to Industrial Developments, Dr. DavidMoratal (ed.). ISBN: 978-953-51-0474-2, In Tech; 2012. 496 p.
[38]. Gaspar M, Weichert F. Integrated construction and simulation of tool paths for milling dental crowns and bridges. Computer-Aided Design. 2013 Oct 1;45(10):1170-81.
[39]. McLean J.W. In: Dental Ceramics. Proceedings of the First International Symposium on Ceramics (McLean J.W.), Chicago: Quintessence Publishing Co; 1984. pp. 13-40.
[40]. Posselt A, Kerschbaum T. Longevity of 2328 chairside Cerec inlays and onlays. Int J Comput Dent. 2003 Jul;6(3):231-48. PubMed PMID: 14601187.
[41]. Scotti R, Catapano S, D'Elia A. A clinical evaluation of In-Ceram crowns. Int J Prosthodont. 1995 Jul-Aug;8(4):320-3. PubMed PMID: 7575973.
[42]. Liu PR, Isenberg BP, Leinfelder KF. Evaluating CAD-CAM generated ceramic veneers. J Am Dent Assoc. 1993 Apr;124(4):59-63. PubMed PMID: 8340547.
[43]. Bindl A, Mörmann WH. Survival rate of mono-ceramic and ceramic-core CAD/CAM-generated anterior crowns over 2-5 years. Eur J Oral Sci. 2004 Apr;112(2):197-204. PubMed PMID: 15056119.
[44]. Lampe K, Luthy H, Mörmann W H. In: CAD/CAM, in Aesthetic Dentistry, Cerec 10 Year Anniversary Symposium (Mörmann W.H.), Chicago, II: Quintessence; 1996. pp. 463-482.
[45]. Degrange M, Sadoun M, Heim N. Dental ceramics. Part 2: The new ceramics. J Biomater Dent. 1987 Mar;3(1):61-9. French.PubMed PMID: 3482834.
[46]. Pröbster L. Four year clinical study of glass-infiltrated, sintered alumina crowns. J Oral Rehabil. 1996 Mar;23(3):147-51. PubMed PMID: 8667118.
[47]. Scotti R, Catapano S, D'Elia A. A clinical evaluation of In-Ceram crowns. Int J Prosthodont. 1995 Jul-Aug;8(4):320-3. PubMed PMID: 7575973.
[48]. Hickel R, Dasch W, Mehl A, Kremers L. CAD/CAM--fillings of the future? Int Dent J. 1997 Oct;47(5):247-58. PubMed PMID: 9448805.
[49]. Blatz MB, Sadan A, Blatz U. The effect of silica coating on the resin bond to the intaglio surface of ProceraAllCeram restorations. Quintessence Int. 2003 Jul-Aug;34(7):542-7. PubMed PMID: 12946074.
[50]. Blatz MB, Sadan A, Martin J, Lang B. In vitro evaluation of shear bond strengths of resin to densely-sintered high-purity zirconium-oxide ceramic after long-term storage and thermal cycling.J Prosthet Dent. 2004 Apr;91(4):356-62. PubMed PMID: 15116037.
[51]. Kunii J, Hotta Y, Tamaki Y, Ozawa A, Kobayashi Y, Fujishima A, Miyazaki T, Fujiwara T. Effect of sintering on the marginal and internal fit of CAD/ CAM-fabricated zirconia frameworks. Dent Mater J. 2007 Nov;26(6):820- 6. PubMed PMID: 18203487.
[52]. SL Campanelli, G Casalino, AD Ludovico, C Bonserio. An artificial neural network approach for the control of the laser milling process. Int J Adv- Manuf Technol. 2013;66:1777–1784.
[53]. Peixin Hu, Lu Yao, Qi Tao Lue, EnCai Ji, et al. The preliminary study based on milling dental glass ceramics with visible and infrared picosecond laser pulse. The International Journal of Advanced Manufacturing Technology. 2020;108 :1029-1038.
[54]. El Gamal A, Fornaini C, Rocca JP, Muhammad OH, Medioni E, Cucinotta A, Brulat-Bouchard N. The effect of CO2 and Nd:YAP lasers on CAD/ CAM Ceramics: SEM, EDS and thermal studies. Laser Ther. 2016 Mar 31;25(1):27-34. PubMed PMID: 27141152.
[55]. Li J, Ji L, Hu Y, Bao Y. Precise micromachining of yttriatetragonalzirconia polycrystal ceramic using 532 nm nanosecond laser. Ceram Int. 2016;42(3):4377-4385.
[56]. Ohkuma K, Kameda T, Terada K. Five-axis laser milling system that realizes more accurate zirconia CAD/CAM crowns by direct milling from fully sintered blocks. Dent Mater J. 2019 Feb 8;38(1):52-60. PubMed PMID: 30224604.
[57]. Kazama-Koide M, Ohkuma K, Ogura H, Miyagawa Y. A new method for fabricating zirconia copings using a Nd:YVO4 nanosecond laser. Dent Mater J. 2014;33(3):422-9. PubMed PMID: 24786345.
[58]. Wang X, Shephard JD, Dear FC, Hand DP. Optimized Nanosecond Pulsed Laser Micromachining of Y-TZP Ceramics. J Am Ceram Soc. 2008 Feb;91(2):391-7.
[59]. Song DB, Han MS, Kim SC, Ahn J, Im YW, Lee HH. Influence of Sequential CAD/CAM Milling on the Fitting Accuracy of Titanium Three-Unit Fixed Dental Prostheses.Materials (Basel). 2021 Mar 13;14(6):1401. Pub- Med PMID: 33805802.
[60]. Li R, Chen H, Wang Y, Sun Y. Performance of stereolithography and milling in fabricating monolithic zirconia crowns with different finish line designs. J MechBehav Biomed Mater. 2021 Mar;115:104255. PubMed PMID: 33340775.