Clinical Evaluation Of The Aesthetic And The Translucency Properties For Porcelain Laminate Veneers Fabricated Using Heat-Pressed And CAD/CAM Techniques
Chaza Kanout*
Lecturer, Department of Prosthodontics, Faculty of Dentistry, Damascus University, Syria.
*Corresponding Author
Chaza Kanout,
Lecturer, Department of Prosthodontics, Faculty of Dentistry, Damascus University, Syria.
E-mail: dr.shazakanout@gmail.com
Received: August 08, 2021; Accepted: September 27, 2021; Published: October 04, 2021
Citation:Chaza Kanout. Clinical Evaluation Of The Aesthetic And The Translucency Properties For Porcelain Laminate Veneers Fabricated Using Heat-Pressed And CAD/CAM Techniques. Int J Dentistry Oral Sci. 2021;8(10):4727-4733. doi: dx.doi.org/10.19070/2377-8075-21000961
Copyright: Chaza Kanout©2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Abstract
Background and Aim of Study: porcelain laminate veneers have become a very common cosmetic choice due to their highly
aesthetic properties in addition to their long-term clinical survival, and considering the various methods of manufacturing the
porcelain laminate veneers it has left the practitioner facing a difficulty when it comes to choosing the best technique there is
for manufacturing veneer, thus the aim of this study is to evaluate the esthetic properties and the translucency of porcelain
laminate veneers that are fabricated with the heat-pressed and the CAD/CAM techniques.
Materials and Methods: The study sample consisted of (60) IPS e.max porcelain laminate veneers (N=60) that have been
done on 7 patients and it was divided into two equal groups (n1=n2=30). In the first group, Porcelain laminate veneers were
fabricated using CAD/CAM technique (IPS e.max CAD), and the second group, Porcelain Laminate veneers were fabricated
using Heat-Pressed technique (IPS e.max Press), whereas they were cemented using light cured resin cement (Variolink N).
the esthetic properties were evaluated according to World Dental Federation (FDI) criterions ( surface shine, surface staining,
esthetic anatomical form) after one week- 3 – 6 – 12 months of the cementation. data analysis was done using Mann-Whitney
U test and using Fisher’s exact test for correlated samples for studying the significance of statistical differences at significance
level (0.05=a).
Results: the results of the evaluation of surface staining and esthetic anatomical form in both of the study groups were clinically
accepted, whereas there were no statistically significant differences during all the follow-up periods, while the surface
shine and translucency in the (IPS e.max CAD) group were less with a statistically significant difference than the (IPS e.max
Press).
Conclusions: within the limits of this study we conclude that (IPS e.max CAD) porcelain laminate veneers have a lesser degree
of surface shine and translucency properties than (IPS e.max Press) porcelain laminate veneers. In addition to that, there
was no detected effect on the esthetic criterion (surface staining and esthetic anatomical form) when using different fabrication
methods of porcelain laminate veneers.
2.Introduction
3.Materials and Methods
3.Results
4.Discussion
5.Conclusion
5.References
Introduction
For several years, Porcelain crowns and porcelain laminate veneers
have been a common option for treating simple cases of
crowded upper anterior teeth of which it affects the aesthetic appearance,
Nevertheless, full porcelain crowns are considered not
conservative [1, 2]. This has led to putting into consideration porcelain
laminate veneers as a preferable esthetical and functional
treatment option for sucha cases as it is more conservative and
it leads to a more aesthetic results [3]. Porcelain laminate veneers
were first introduced as the first aesthetic treatment option in the
early year of 1980 AD [4].
Reaching excellent aesthetic results using porcelain laminate veneers
is known to have its’ difficulties for dentists, this is due to
the complicated visual properties of the different shades of natural
teeth, it requires a good knowledge of the basic principles and
the visual properties of the restoration materials in order to reach
successful aesthetic restorations [5], in addittion, the process itself
of manufacturing porcelain restorations with shades as close as
possible to natural teeth shades is considered a true challenge in
dentistry [6].
For several years, feldspathic ceramic have been considered one
of the best materials to be used in fabricating porcelain laminate
veneers due to the advanced aesthetic properties of it [7], nevertheless, the constant updates and developments that were applied
on the porcelain materials, the glass ceramic reinforced with
lithium disilicate crystals (IPS e.max) have now become the best
option to be used in fabricating veneers because of its’ bending
resistance properties in addition to the excellent aesthetic properties
[8].
Porcelain laminate veneers with glass ceramic base (IPS e.max) are
fabricated using either the Heat-Pressed technique which come in
an ingots form that are later pressed after melting the wax model
using the conventional lost wax technique, then the ceramic ingots
are fused and pressed under a controlled heat and press, using
computer programmed press ovens (IPS e.max Press), or the
porcelain laminate veneers are fabricated using computer aided
design and manufacturing (CAD/CAM) which they come in a
blocks form that are partially crystalized and mechanically carved,
this process doesn’t take more than a few taps on the keyboard
in order to design and manufacture a highly accurate restoration
(IPS e.max CAD)[10, 11].
There are many factors affecting the shade of dental restorations
such as: fabricating technique, baking process, glazing, liquid to
powder ratio, oral cavity environment circumstances, and aging
[12, 13].
Several studies have evaluated the aesthetic properties of porcelain
laminate veneers fabricated using feldspathic ceramic [14, 15],
nevertheless, there was a lack of information regarding the evaluation
of the aesthetic and translucency properties of porcelain
laminate veneers with a glass ceramic base (IPS e.max) fabricated
using Heat-pressed technique and (CAD/CAM) technique, therefor,
the main subject of this study was considered to be the clinical
evaluation of the aesthetic and translucency properties of porcelain
laminate veneers fabricated using Heat-pressed technique
and computer aided design and manufacturing (CAD/CAM).
Materials And Methods
The study sample consisted of 60 IPS e.max porcelain laminate
veneers divided into two groups:
First group: consisted of 30 IPS e.max porcelain laminate veneers
fabricated using computer aided design and manufacture technique
CAD/CAM.
Second group: consisted of 30 IPS e.max porcelain laminate veneers
fabricated using Heat-Pressed technique.
The veneers were applied on 7 regular visitors to the fixed prosthodontics
department in Damascus University Faculty of Dentistry
who suffer from aesthetic problems in their teeth appearances,
the age range was between 21 and 49 years old.
The admission criteria were that the patient age must be between
18 and 50 years old, and the patient must have an obvious indication
for porcelain laminate veneers (teeth shape and size modification,
slightly stained teeth, simple cases of diastema, simple cases
of teeth crowding or titled teeth, simple fractures, enamel defaults
or having poorly applied dental restorations), in addition to that,
the gingiva and the periodontal tissues must be in a healthy condition,
there must be a normal anterior occlusion bite, good oral
hygiene and the patient approval to participate in follow up tests.
The demission criteria consisted of having big previous restorations,
teeth suffering from extended fractures, endodontic treated
teeth, the loss of inferior teeth support and patients who suffer
from high caries rate.
First, the main complaint and patient history were taken and the
realization of the expected aesthetic result was created in mind
and the form which was created for the sake of this scientific
study was filled by each patient, the form contained information
that relates to the purpose of this study, information about general
and medical history of the patient plus the patients’ written
approval, in addition, extra oral and intra oral examination were
performed and intra oral pictures and pictures of the smiling status
were taken.
Teeth were prepared to receive porcelain laminate veneers using
the bevel incisal preparation, margins were finished using smooth
conical bur after putting in the gingival retraction cords in order
to reach an accurate and precise finishing line [16] (Fig.1).
Final impression was taken using additional silicone and the opposite
arch impression was taken using alginate, in addition to the
wax bite of the prepared teeth.
Following steps include choosing a suitable shade using teeth
shade guide and having the patients’ approval and document that
shade, temporary prosthesis were made using intra oral acrylic.
Regarding the porcelain laminate veneers fabricated using computer
aided design and manufacture CAD/CAM technique, at the
beginning, a powder spray was applied on the surface of the prepared
teeth cast model dies for scanning purposes, a laser digital
scanning process was performed using a 3D camera connected
to the device (CCD), utilizing the designing program (3D inLab)
a 3D picture of the cast model was obtained on the computer
screen which is also connected to the laser scanner device.
Finishing lines of the preparation were defined on the digital hypothetical
cast leaving a hypothetical space for the luting cement
around 40 micron, and then the anatomical modifications were
made on the porcelain laminate veneers using special features of
the designing program (Fig.2).
After finishing the designing process, the IPS e.max CAD block
(which has the right shade and translucency for each case) is
placed tightly in its’ alleged place in the carving device InLab MC
LX, when the carving order is given the process starts under cooling
with cold water (Fig.3).
When the chamber lights turn green it means that the carving
process has ended successfully and it’s time to open the chamber
lid and take out the carved block.
Each veneer is then separated from the remaining section of the
Block using specific separating disks, whereas the porcelain laminate
veneers is now unhardened completely and have a blue color
shade (Fig.4).
The porcelain laminate veneers are placed in a hardening oven
(Programt P500) in order for the crystallization to begin, with
heating degree up to 840-850 C for 15 minutes, the hardening and the crystallization processes are considered to be easy and cause
no following shrinkages [17].
The inner structure of the porcelain laminate veneers gain its’
solidness and its’ shade when the hardening process is over, after
that, veneers are covered with glass ceramic which contains Fluor
apatite crystals (IPS e.maxceram) in order to have the desired high
aesthetic result, the final step is glazing.
Before final cementation, provisional prostheses are removed and
porcelain laminate veneers are placed to evaluate proper fitting of
the restorations in addition to the evaluation of a pleasing shade,
after taking the patients’ approval of the aesthetic outcome of
the porcelain laminate veneers, final cementation of the veneers
is performed, intaglio surfaces are etched using hydrofluoric acid
(Ultradent) with 9% concentration for 90 seconds according to
the manufacturing company instructions, then washed with running
water and dried with airflow, double bonding agent is applied
(MonoBond S) for 60 seconds, spreaded using a slight airflow
only.
Regarding prepared abutments, for isolated working area mouth
opener was applied in addition to cotton roles and saliva suction,
prepared surfaces were etched using phosphoric acid with 37%
concentration for 30 seconds, washed with flowing water and
dried with airflow till the chalky appearance was obvious.
Dentin bonding agent (Tetric-N Bond) was applied on prepared
surfaces then spreaded using a slight airflow only, resin light cured
cement (Variolink N) is then applied on the intaglio surface of
the porcelain laminate veneers and properly spreaded on the
whole inner surface, porcelain laminate veneer are then placed on
the right abutments for each one, accurate fitting was evaluated
through direct site and marginal adaptation.
Resin cement was light cured from the buccel and the palatal approach
for 3-4 seconds only to have the cement at its’ pasty phase,
this was done to ease removing the excess cement using dental
probe and surgical blade type 12, excess cement in the proximal
areas was removed using dental floss.
Then, resin cement was light cured from abuccel, palatal and incisal
approach for 60 seconds per each, margins were finished using
extremely soft diamond finishing burs, and soft abrasive strips
for the proximal areas (Fig. 5).
The required data of each case were registered in the form of
each patient during the permanent cementation visit, theses clinical
cases had then follow up visits a week, 3 months, 6 months,
and 12 months after cementation, the cases were evaluated by two
practitioners independent from the researcher without informing
them with the fabricating techniques used for the porcelain
laminate veneers, the practitioners were taught how to perform
the evaluation, a third practitioner was required when having a
disagreement on a certain point of the evaluation.
First, surface luster and roughness were evaluated by visually
comparing them with natural luster and roughness of the enamel
of the adjacent teeth, the process was preformed without the dental
chair light source. Numbers were given to each observed case
according to Hickel (2010) [18] listed in the following Table (1).
Surface staining of the porcelain laminate veneers was visually
evaluated by comparing with the adjacent teeth surfaces. Numbers
were given to each observed case according to Hickel (2010)
listed in the following Table (1).
Anatomical form of the PLV was evaluated by noticing its’ effect
on the general aesthetic appearance. Numbers were given to each
observed case according to Hickel (2010) listed in the following
Table (1).
Finally, the residents were asked questions with a Yes or No answer
for evaluation translucency, esthetic appearance and shade
listed in the following Table (2).
Results
Seven patients participated, and a total of 61 PLVs were evaluated
in this study.
Study sample consisted of 60 IPS e.maxPLVs divided into two
equal groups:
Surface luster in all of the PLVs at both study groups (IPS e.max
CAD, IPS e.max Press) was close to natural enamel luster, except
for one PLV in the IPS .max CAD group after one week (3%),
and 5 other PLVs in the same group after 3, 6, and 12 months of
follow up, the surface of these veneers was slightly dull but isn’t
notable from speaking distance.
There were no statistically significance difference between the
two groups after one week of follow up (p=0.317), whereas the
PLVs of the IPS e.max CAD group presented less surface luster
than the IPS e.max heat-Pressed group after 3, 6, and 12 months
of follow up with a statistically significant difference (p= 0.021)
Table (3).
No surface staining cases were detected in both study groups (IPS
e.max CAD, IPS e.max Press) during all of the follow up sessions
(after one week, 3, 6, and 12 months).
Aesthetic anatomical form was ideal in the IPS e.max CAD group
during all of the follow up periods, whereas the aesthetic anatomical
form was slightly different from the natural appearance in
7% of the PLVs in the IPS e.max Press group, nevertheless, all of
the other PLVs in this study group had ideal aesthetic anatomical
form during follow ups.
33% of the PLVs (IPS e.max CAD) group had differences in
translucency, whereas no differences were found in the PLVs (IPS
e.max Press) group during follow ups Table (4).
Chi-squared test was used to study translucency differences between
study groups during follow ups. Translucency differences
values of the CAD/CAM group were greater by 33% than the
values of the Heat-Pressed group with a statistically significant
difference (p> 0.0005).
There were no aesthetical nor color differences in the PLVs between
the two study groups.
Table 2. Questions asked by residents and answered with yes or no for evaluation translucency, esthetic appearance and shade.
Table 3. The Mann–Whitney U test to study the difference in surface luster for both study groups (n= 60).
Discussion
PLVs fabrication techniques have varied throughout the years,
originally they were made using the layering technique, nevertheless,
this technique required a lot of time and effort in order to
make an accurate fit of the restoration on the prepared tooth [19].
New generations have presented new porcelain materials to Dentistry
that used Heat-Pressed technique, whereas this technique
also required great time and effort due to the process of waxing,
melting, molding, carving, and heat-pressing and it needs a highly
skilled technician to carve the aesthetic anatomical details and to
insure good inner and marginal fit [20, 21], but with the rapid
evolution of the digital computer technology and the new generations
of porcelain materials that are now presented in blocks
form capable of being carved, this has led to the usage of computer
aided design and manufacturing systems (CAD/CAM) in
fabricating PLVs, which don’t require more than a few taps on
the keyboard to design and manufacture a highly adapted restoration,
therefore reducing time and effort comparing to previous
techniques [22].
Glass ceramic reinforced with lithium disilicate crystals system
was adopted (IPS e.max) in this study due to it being clinically
accepted and has better mechanical properties than the traditional
feldisbaric ceramic, in addition to its’ high aesthetic and translucency
qualities without affecting the hardness and durability of
the PLV [7].
Functional properties were evaluated using World Dental Federation
(FDI) criterias considering these criterias to be flexible, easy,
practical, and unified, plus they are more accurate and more sensitive
to detecting differences in restorations [24, 25].
The surface of PLVs fabricated using (CAD/CAM) technique
had less luster than the surface of PLVs fabricated using Heat-
Press technique after 3, 6, and 12 months of follow ups, after
investigating the cause of this very slight roughness, it appeared
to be due to wrong teeth brushing techniques performed by these
patients, this minor roughness was especially detected in the PLVs
that are cemented on the premolars which they receive excessive
brushing force compered to anterior PLVs which are on the incisors
[26].
The results of this study agreedwith the results of a study made
in 2020 by Souza et al where they noticed that onlays (IPS e.max
CAD) had slight roughness according to FDI criterias, and it was
due to the removal of the glazing layer during occlusion modifications
after cementing the restoration [27].
No surface staining was detected in both study groups during
follow ups, this was due to patients not having acidic foods and
drinks with excessive amounts and not having a history of illnesses
causing acidic oral environment such as chronic vomiting,
in addition to the process of manufacturing the ingots and blocks
of the glass ceramic containing of lithium disilicate crystals that
is performed ideally in a way that prevents pores creation, which
blocks the absorption of oral fluids and pigments [17, 28].
Aesthetic anatomical form of the PLVs was ideal in both study
groups except two veneers that were slightly different form the
natural appearance (grade 2 of the FDI criterias), but there was
no statistically significant difference between the study groups,
the reason might be due to the usage of covering porcelain (IPS
e.maxceram) on the cores of the PLVs in both study groups,
which is considered having high visual, aesthetic, and translucency
properties.
PLVs fabricated using CAD/CAM technique had less translucency
than PLVs fabricated using Heat-Pressed technique despite of
the color matching, the reason might be because of the crystallization
process is partial at the beginning in the PLVs fabricated
using CAD/CAM technique, whereas the coloring elements experience
an oxidation state at this phase, the PLVs are blue or
grayish blue at this point and after the full crystallization has ended
they gain the required color and translucency [29], in addition
to that, there might be another reason which is due to the different
microbial structure of each porcelain type, IPS e.max Press
has crystals size range from 3 to 6 microns, whereas IPS e.max
CAD has crystals size range from 0.8 to 1.5 microns, because of
the same crystals percent in both porcelain types, the porcelain
that has larger crystals, they tend to be less in number and density
therefore higher translucency [10].
This study results agreed with the results of a study made by
Tuncdemir et al which reported that PLVs fabricated using CAD/
CAM technique had greater color changes than PLVs fabricated
using Heat-Pressed technique, this was due to lack of accurate
marginal adaptation which leads to micro leakage, in addition to
using dual-cured resin in the cementation of PLVs [30].
Conclusion
Within the limits of this study, the following was concluded:
PLVs fabricated using CAD/CAM technique had less luster and
translucency than PLVs fabricated using Heat-Press technique.
No differences were detected between the two fabricating techniques
of the PLVs regarding: surface staining and aesthetic anatomical
form.
Recommendations
Glass ceramic reinforced with lithium desilicate crystals (IPS
e.max) is recommended in fabricating PLVs because of the high
mechanical, translucency, and aesthetical properties.
IPS e.max Press is recommended In cases that require high aesthetical
appearance because of its’ high luster and translucency
properties.
References
-
[1]. Calamia JR, Calamia CS. Porcelain laminate veneers: reasons for 25 years of
success. Dent Clin North Am. 2007 Apr;51(2):399-417. PMID: 17532919.
[2]. Walls AW, Steele JG, Wassell RW. Crowns and other extra-coronal restorations: porcelain laminate veneers. Br Dent J. 2002 Jul 27;193(2):73-6, 79- 82. PMID: 12199127.
[3]. Piwowarczyk A, Blum J, Abendroth H. Non-prep restoration of an ankylosed incisor: a case report. Quintessence Int. 2015 Apr;46(4):281-5. PMID: 25642458.
[4]. Alavi AA, Behroozi Z, Nik Eghbal F. The Shear Bond Strength of Porcelain Laminate to Prepared and Unprepared Anterior Teeth. J Dent (Shiraz). 2017 Mar;18(1):50-55. PMID: 28280760.
[5]. Vichi A, Louca C, Corciolani G, Ferrari M. Color related to ceramic and zirconia restorations: a review. Dent Mater. 2011 Jan;27(1):97-108. PMID: 21122905.
[6]. Haralur SB, Alfaifi M, Almuaddi A, Al-Yazeedi M, Al-Ahmari A. The Effect of Accelerated Aging on the Colour Stability of Composite Resin Luting Cements using Different Bonding Techniques. J Clin Diagn Res. 2017 Apr;11(4):ZC57-ZC60. PMID: 28571263.
[7]. Barizon KT, Bergeron C, Vargas MA, Qian F, Cobb DS, Gratton DG, Geraldeli S. Ceramic materials for porcelain veneers: part II. Effect of material, shade, and thickness on translucency. The Journal of prosthetic dentistry. 2014 Oct 1;112(4):864-70.
[8]. da Cunha LF, Pedroche LO, Gonzaga CC, Furuse AY. Esthetic, occlusal, and periodontal rehabilitation of anterior teeth with minimum thickness porcelain laminate veneers. J Prosthet Dent. 2014 Dec;112(6):1315-8. PMID: 25156092.
[9]. Aboushelib MN, Elmahy WA, Ghazy MH. Internal adaptation, marginal accuracy and microleakage of a pressable versus a machinable ceramic laminate veneers. J Dent. 2012 Aug;40(8):670-7. PMID: 22542500.
[10]. Denry I, Holloway JA. Ceramics for dental applications: a review. Materials 2010;3(1):351-68.
[11]. Anadioti E, Aquilino SA, Gratton DG, Holloway JA, Denry IL, Thomas GW, et al. Internal fit of pressed and computer-aided design/computeraided manufacturing ceramic crowns made from digital and conventional impressions. J Prosthet Dent. 2015 Apr; 113(4): 304-9. PMID: 25488521.
[12]. Bagis B, Turgut S. Optical properties of current ceramics systems for laminate veneers. J Dent. 2013 Aug;41 Suppl 3:e24-30. PMID: 23201410.
[13]. Adusumilli H, Avula JS, Kakarla P, Bandi S, Mallela GM, Vallabhaneni K. Color stability of esthetic restorative materials used in pediatric dentistry: An in vitro study. J Indian Soc Pedod Prev Dent. 2016 Jul-Sep;34(3):233-7. PMID: 27461806.
[14]. Smales RJ, Etemadi S. Long-term survival of porcelain laminate veneers using two preparation designs: a retrospective study. Int J Prosthodont. 2004 May-Jun;17(3):323-6. PMID: 15237880.
[15]. Morimoto S, Albanesi RB, Sesma N, Agra CM, Braga MM. Main Clinical Outcomes of Feldspathic Porcelain and Glass-Ceramic Laminate Veneers: A Systematic Review and Meta-Analysis of Survival and Complication Rates. Int J Prosthodont. 2016 Jan-Feb;29(1):38-49. PMID: 26757327.
[16]. Gurel G, Sesma N, Calamita MA, Coachman C, Morimoto S. Influence of enamel preservation on failure rates of porcelain laminate veneers. Int J Peri odontics Restorative Dent. 2013 Jan-Feb;33(1):31-9. PMID: 23342345.
[17]. Tysowsky GW. The science behind lithium disilicate: a metal-free alternative. Dent Today. 2009 Mar;28(3):112-3. PMID: 19323326.
[18]. Hickel R, Peschke A, Tyas M, Mjör I, Bayne S, Peters M, et al. FDI World Dental Federation: clinical criteria for the evaluation of direct and indirect restorations-update and clinical examples. Clin Oral Investig. 2010 Aug;14(4):349-66. PMID: 20628774.
[19]. Taskonak B, Anusavice KJ, Mecholsky JJ Jr. Role of investment interaction layer on strength and toughness of ceramic laminates. Dent Mater. 2004 Oct;20(8):701-8. PMID: 15302450.
[20]. Calamia JR. Etched porcelain facial veneers: a new treatment modality based on scientific and clinical evidence. N Y J Dent. 1983 Sep-Oct;53(6):255-9. PMID: 6355932.
[21]. Shuman IE. Aesthetic treatment with a pressed ceramic veneer material. Dentistry today. 2004 Nov 1;23(11):80-2.
[22]. Fasbinder DJ. Materials for chairside CAD/CAM restorations. Compend Contin Educ Dent. 2010 Nov-Dec;31(9):702-4, 706, 708-9. PMID: 21197938..
[23]. Kurt M, Turhan Bal B. Effects of accelerated artificial aging on the translucency and color stability of monolithic ceramics with different surface treatments. J Prosthet Dent. 2019 Apr;121(4):712.e1-712.e8. PMID: 30929661.
[24]. Kim D, Ahn SY, Kim J, Park SH. Interrater and intrarater reliability of FDI criteria applied to photographs of posterior tooth-colored restorations. J Prosthet Dent. 2017 Jul;118(1):18-25.e4. doi: 10.1016/j.prosdent. 2016.10.004. Epub 2016 Dec 23. PMID: 28024817.
[25]. Yudina NA, Maniuk ON. Otsenka kachestva ésteticheskikh restavratsii po kriteriiam FDI [Quality assessment of aesthetic restorations according to FDI criteria]. Stomatologiia (Mosk). 2020;99(1):18-26. PMID: 32125297.
[26]. Rosentritt M, Sawaljanow A, Behr M, Kolbeck C, Preis V. Effect of tooth brush abrasion and thermo-mechanical loading on direct and indirect veneer restorations. Clin Oral Investig. 2015 Jan;19(1):53-60. PMID: 24578230.
[27]. Souza J, Fuentes MV, Baena E, Ceballos L. One-year clinical performance of lithium disilicate versus resin composite CAD/CAM onlays. Odontology. 2021 Jan;109(1):259-270. PMID: 32705420.
[28]. Vivadent I. IPS e. max CAD. Scientific Documentation, Schaan, Liechtenstein. 2011.
[29]. Tysowsky GW. Evidence-based testing and its applications to dental product development. The journal of evidence-based dental practice. 2010 Mar;10(1):8-9.
[30]. Tuncdemir MT, Gulbahce N, Aykent F. Comparison of color stability of two laminate veneers cemented to tooth surfaces with and without preparation. J Esthet Restor Dent. 2020 Sep;32(6):554-559. PMID: 31925892.