International Journal of Bioorganic Chemistry & Molecular Biology (IJBCMB)    IJBCMB-2332-2756-06-002e

Small-Angle Neutron Scattering (SANS) and Wide-Angle X-Ray Diffraction (WAXD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation



Alireza Heidari*

Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604, USA.

*Corresponding Author

Alireza Heidari,
Faculty of Chemistry, California South University,
14731 Comet St. Irvine, CA 92604, USA.
E-mail: Scholar.Researcher.Scientist@gmail.com;

Received: February 24, 2018; Published: March 01, 2018

Citation: Heidari A. Small-Angle Neutron Scattering (SANS) and Wide-Angle X-Ray Diffraction (WAXD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. Int J Bioorg Chem Mol Biol. 2018;6(2e):1-6. DOI : dx.doi.org/10.19070/2332-2756-180009e

Copyright: Heidari A© 2018. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.




In the current study, we have experimentally and comparatively investigated and compared malignant human cancer cells and tissues before and after irradiating of synchrotron radiation using Small-Angle Neutron Scattering (SANS) and Wide-Angle X-Ray Diffraction (WAXD), It is clear that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passing of time (Figures 1 and 2) [1-135].


Figure 1. Small-Angle Neutron Scattering (SANS) analysis of malignant human cancer cells and tissues (a) before and (b) after irradiating of synchrotron radiation in transformation process to benign human cancer cells and tissues with the passing of time [1-135].



Figure 2. Wide-Angle X-Ray Diffraction (WAXD) analysis of malignant human cancer cells and tissues (a) before and (b) after irradiating of synchrotron radiation in transformation process to benign human cancer cells and tissues with the passing of time [1-135].


It can be concluded that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passing of time (Figures 1 and 2) [1-135].



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  102. Heidari A. Pros and Cons Controversy on Molecular Imaging and Dynamics of Double–Standard DNA/RNA of Human Preserving Stem Cells–Binding Nano Molecules with Androgens/Anabolic Steroids (AAS) or Testosterone Derivatives through Tracking of Helium–4 Nucleus (Alpha Particle) Using Synchrotron Radiation. Arch Biotechnol Biomed. 2017;1(1):067-100.
  103. Heidari A. Visualizing Metabolic Changes in Probing Human Cancer Cells and Tissues Metabolism Using Vivo 1H or Proton NMR, 13C NMR, 15N NMR and 31P NMR Spectroscopy and Self–Organizing Maps under Synchrotron Radiation. SOJ Mater Sci Eng. 2017;5(2):1-6.
  104. Heidari A. Cavity Ring–Down Spectroscopy (CRDS), Circular Dichroism Spectroscopy, Cold Vapour Atomic Fluorescence Spectroscopy and Correlation Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. Enliven: Challenges Cancer Detect Ther. 2017;4(2):e001.
  105. Heidari A. Laser Spectroscopy, Laser-Induced Breakdown Spectroscopy an d LaserInduced Plasma Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. Int J Hepatol Gastroenterol. 2017;3(4):079-84.
  106. Heidari A. Time–Resolved Spectroscopy and Time–Stretch Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. Enliven: Pharmacovigilance and Drug Safety. 2017;4(2):e001.
  107. Heidari A. Overview of the Role of Vitamins in Reducing Negative Effect of Decapeptyl (Triptorelin Acetate or Pamoate Salts) on Prostate Cancer Cells and Tissues in Prostate Cancer Treatment Process through Transformation of Malignant Prostate Tumors into Benign Prostate Tumors under Synchrotron Radiation. Open J Anal Bioanal Chem. 2017;1(1):021-6.
  108. Alireza Heidari, “Electron Phenomenological Spectroscopy, Electron Paramagnetic Resonance (EPR) Spectroscopy and Electron Spin Resonance (ESR) Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation”, Austin J Anal Pharm Chem. 2017; 4(3):1091.
  109. Heidari A. Therapeutic Nanomedicine Different High–Resolution Experimental Images and Computational Simulations for Human Brain Cancer Cells and Tissues Using Nanocarriers Deliver DNA/RNA to Brain Tumors under Synchrotron Radiation with the Passage of Time Using Mathematica and MATLAB. Madridge J Nano Tech. 2017 Nov 24;2(2):77-83.
  110. Heidari A. A Consensus and Prospective Study on Restoring Cadmiu m Oxide (CdO) Nanoparticles Sensitivity in Recurrent Ovarian Cancer b y Extending the Cadmium Oxide (CdO) Nanoparticles-Free Interval Usin g Synchrotron Radiation Therapy as Antibody-Drug Conjugate for the Treatment of Limited–Stage Small Cell Diverse Epithelial Cancers. Cancer Clin Res Rep. 2017;2.
  111. Heidari A. A Novel and Modern Experimental Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under White Synchrotron Radiation. Cancer Sci Res Open Access. 2017;4(2):1-8.
  112. Heidari A. Different High-Resolution Simulations of Medical, Medicinal, Clinical, Pharmaceutical and Therapeutics Oncology of Human Lung Cancer Translational Anti-Cancer Nano Drugs Delivery Treatment Process under Synchrotron and X-Ray Radiations. J Med Oncol. 2017;1(1):1.
  113. Heidari A. Vibrational Decihertz (dHz), Centihertz (cHz), Millihertz (mHz), Microhertz (μHz), Nanohertz (nHz), Picohertz (pHz), Femtohertz (fHz), Attohertz (aHz), Zeptohertz (zHz) and Yoctohertz (yHz) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. J Biomed. 2017 Dec 1;7(4):335-40.
  114. Heidari A. Force Spectroscopy and Fluorescence Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. EC Cancer. 2017;2:239-46.
  115. Heidari A. Photoacoustic Spectroscopy, Photoemission Spectroscopy and Photothermal Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time Under Synchrotron Radiation. BAOJ Cancer Res Ther. 2017 3: 045.
  116. Heidari A. J-Spectroscopy, Exchange Spectroscopy (EXSY), Nucle¬ ar Overhauser Effect Spectroscopy (NOESY) and Total Correlation Spectroscopy (TOCSY) Comparative Study on Malignant and Benign Human- Cancer Cells and Tissues under Synchrotron Radiation. EMS Eng Sci J. 2017;1(2):006-13.
  117. Heidari A. Neutron Spin Echo Spectroscopy and Spin Noise Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. Int J Biopharm Sci. 2018;1:103.
  118. Heidari A. Vibrational Decahertz (daHz), Hectohertz (hHz), Kilohertz (kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz (PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. Madridge J Anal Sci Instrum. 2017;2(1):41-46.
  119. Heidari A. Two-Dimensional Infrared Correlation Spectroscopy, Linear TwoDimensional Infrared Spectroscopy and Non-Linear Two-Dimensional Infrared Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time. J Mater Sci Nanotechnol. 2018;6(1): 101.
  120. Heidari A. Fourier Transform Infrared (FTIR) Spectroscopy, Near–Infrared Spectroscopy (NIRS) and Mid–Infrared Spectroscopy (MIRS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time. Int J Nanotechnol Nanomed. 2018;3(1):1-6.
  121. Alireza Heidari, “Infrared Photo Dissociation Spectroscopy and Infrared Correlation Table Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time”, Austin Pharmacol Pharm. 2018;3(1): 1011.
  122. Heidari A. Novel and Transcendental Prevention, Diagnosis and Treatment Strategies for Investigation of Interaction among Human Blood Cancer Cells, Tissues, Tumors and Metastases with Synchrotron Radiation under Anti–Cancer Nano Drugs Delivery Efficacy Using MATLAB Modeling and Simulation. Madridge J Nov Drug Res. 2017;1(1):18-24.
  123. Heidari A. Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. Open Access J Trans Med Res. 2018;2(1):00026–00032.
  124. Marcia G, Ricardo G, Heidari A. Planting of Jaboticaba Trees for Landscape Repair of Degraded Area. Landscape Architecture and Regional Planning. 2018;3(1):1-9.
  125. Heidari A. Correlation Two–Dimensional Nuclear Magnetic Resonance (NMR) (2D–NMR) (COSY) Imaging and Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. EMS Cancet Sci J. 2018;1(1):001.
  126. Heidari A. Fluorescence Spectroscopy, Phosphorescence Spectroscopy and Luminescence Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation with the Passage of Time. SM J Clin. Med. 2018;4(1):1018.
  127. Heidari A. Nuclear Inelastic Scattering Spectroscopy (NISS) and Nuclear Inelastic Absorption Spectroscopy (NIAS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. Int J Pharm Sci. 2018;2(1):1–14.
  128. Heidari A. X–Ray Diffraction (XRD), Powder X–Ray Diffraction (PXRD) and Energy–Dispersive X–Ray Diffraction (EDXRD) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. J Oncol Res. 2018;2(1):1-14.
  129. Heidari A. Thermal Spectroscopy, Photothermal Spectroscopy, Thermal Microspectroscopy, Photothermal Microspectroscopy, Thermal Macrospectroscopy and Photothermal Macrospectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. SM J Biometrics Biostat. 2018; 3(1):1024.
  130. Heidari A. A Modern and Comprehensive Experimental Biospectroscopic Comparative Study on Human Common Cancers’ Cells, Tissues and Tumors before and after Synchrotron Radiation Therapy. Open Acc J Oncol Med. 2018;1(1).
  131. Heidari A. Heteronuclear Correlation Experiments such as Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple– Quantum Correlation Spectroscopy (HMQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Endocrinology and Thyroid Cancer Cells and Tissues under Synchrotron Radiation. J Endocrinol Thyroid Res. 2018;3(1):555603.
  132. Heidari A. Nuclear Resonance Vibrational Spectroscopy (NRVS), Nuclear Inelastic Scattering Spectroscopy (NISS), Nuclear Inelastic Absorption Spectroscopy (NIAS) and Nuclear Resonant Inelastic X–Ray Scattering Spectroscopy (NRIXSS) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. Int J Bioorg Chem Mol Biol. 2018 Feb 7;6(1e):1-5.
  133. Heidari A. A Novel and Modern Experimental Approach to Vibrational Circular Dichroism Spectroscopy and Video Spectroscopy Comparative Study on Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under White and Monochromatic Synchrotron Radiation. Glob J Endocrinol Metab. 2018;1(3):000514–000519.
  134. Heidari A. Pros and Cons Controversy on Heteronuclear Correlation Experiments such as Heteronuclear Single–Quantum Correlation Spectroscopy (HSQC), Heteronuclear Multiple–Quantum Correlation Spectroscopy (HMQC) and Heteronuclear Multiple–Bond Correlation Spectroscopy (HMBC) Comparative Study on Malignant and Benign Human Cancer Cells and Tissues under Synchrotron Radiation. EMS Pharma J. 2018;1(1):002–008.
  135. Heidari A. A Modern Comparative and Comprehensive Experimental Biospectroscopic Study on Different Types of Infrared Spectroscopy of Malignant and Benign Human Cancer Cells and Tissues with the Passage of Time under Synchrotron Radiation. J Analyt Molecul Tech. 2018;3(1):8.

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